Demand for weight-loss drugs such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) is growing, raising concerns about environmental contamination from millions of prefilled plastic pens.[1] The US almost exclusively uses single-dose pens that are thrown away after one use, while most of Europe uses multi-dose pens.[1] Prefilled pens are more user-friendly and allow treatment at home without the supervision of medical personnel.[1] However, home treatment can lead to improper waste disposal because the public is not trained in the proper disposal of clinical waste, unlike healthcare facilities.[1] According to Matthew Parker of the Technology Partnership in Cambridge, medical waste is more likely to be disposed of correctly in a hospital environment due to the training provided.[1]