People with HIV did not have a significant increase in depressive symptoms after starting semaglutide (Ozempic, Wegovy, Rybelsus) for diabetes or weight loss, according to a nine-month observational study. The study was conducted over a median period of time. Semaglutide is not associated with depressive symptoms in people with HIV. The results show the absence of a significant increase in depression after starting treatment. The study was presented in Denver, according to MedPage Today.