The United States achieved measles-free status in 2000, but health authorities fear it will now lose it[1]. The measles epidemic in the US has been ongoing for more than 12 months, and in 2025 they recorded over 2,200 cases with three deaths, including two young children[5][2]. This is the worst annual number of cases in more than 30 years[2]. Most of the infected were not vaccinated, for example in South Carolina 646 cases since the fall, of which 88 since January 16[1]. By March 2025, 301 confirmed cases had been reported in 15 states, with 95% of those infected either unvaccinated or unable to verify vaccination[3]. The Pan American Health Organization will review the status of the US and Mexico in April[1]. Canada lost its status in November 2025 after over 5,000 cases[1]. The increase in cases continues even in 2026[5].