Oregon State University scientists have developed a new iron-based nanomaterial that destroys cancer cells through chemical reactions without harming healthy tissue.[1][2] This material is a metal-organic framework (MOF) that uses the acidic environment and high levels of hydrogen peroxide in cancer cells to trigger chemodynamic therapy (CDT).[1][2] The nanomaterial generates both hydroxyl radicals and singlet oxygen, thereby creating reactive oxygen species and causing oxidative stress in tumors.[1][2] The study, led by Oleh and Olenena Taratul and Chao Wang, was published in the journal Advanced Functional Materials.[1][2] In tests on mice with human breast cancer cells, the nanoagent accumulated in tumors, completely eradicated them, and prevented recurrence without toxicity.[1][2] The nanomaterial has shown strong toxicity against multiple cancer cell lines, but minimal damage to healthy cells.[1][2] The researchers plan tests on other types of cancer, including pancreatic, before clinical trials in humans.[1][2]