Surgery is a common cause of chronic pain, and current treatments for chronic postoperative pain (CPSP) produce suboptimal results with slow progress. The study used a bibliometric analysis of CPSP literature published from January 1, 2004 to August 5, 2025 from the Web of Science and Scopus databases. A total of 1,211 eligible English-language articles and reviews were screened, analyzing publication trends, countries, institutions, authors, journals, and keywords. Annual publications on CPSP from 2004 to 2025 show an upward trend, with the US, China, Canada, and Denmark being the most productive countries. Keyword analysis revealed “risk factor,” “chronic postoperative pain,” and “pain management” as major research foci. The highly cited authors and journals were mostly concentrated in North America and Europe. Research into CPSP is expanding, but effective treatment options remain limited. Future studies should strengthen multidisciplinary collaboration to better understand the pathogenesis of CPSP and develop more effective interventions.[2]