Bleeding after pancreaticoduodenectomy (PPH) is a serious complication of laparoscopic pancreaticoduodenectomy (LPD), while segmental hepatic necrosis after transarterial embolization is extremely rare. In this case, late intra-abdominal bleeding occurred after LPD, which was treated with common hepatic artery embolization under digital subtraction angiography (DSA). Forty days after embolization, necrotic tissue was spontaneously released from the laparotomy wound, and histopathology confirmed devitalized liver parenchyma. The patient recovered well thanks to conservative wound care, drainage and irrigation. Liver necrosis may have resulted from a lack of collaterals in the left lobe, leading to insufficient perfusion and ischemia. The case highlights the importance of preoperative imaging in LPD to accurately delineate the vascular anatomy of the liver and plan treatment for PPH.