The study analyzed 412 pregnant women with fetal growth restriction (FGR) from 2022–2023, comparing the favorable and unfavorable prognosis groups.[1] The unfavorable prognosis group had lower birth scores and were born at an earlier gestational age.[1] Placental function indices (Flow Index, Vascularization Index, and Vascularization Flow Index) were significantly higher in the favorable group, while umbilical artery Doppler parameters (pulsatility index, resistance index, and systolic/diastolic ratio) were lower in this group.[1] Umbilical cord blood analysis showed higher values of pH, pO2 and HCO3− with lower pCO2 in the favorable group.[1] Multivariate analysis identified elevated Doppler parameters and pCO2 as risk factors for adverse outcome, while higher pH, pO2 and HCO3− were protective factors.[1] The created predictive model achieved an accuracy of 79.5% (AUC 0.795) with a sensitivity of 68.6% and a specificity of 78.1%.[1] The findings emphasize the importance of comprehensive monitoring of placental function and cord blood parameters in FGR.[1]