Glucocorticoids act by suppressing the activity of immune cells, thereby increasing the risk of infection. This risk persists even at daily doses lower than 5 mg of prednisone equivalent. The article describes the first documented case of a patient with bullous pemphigoid. After glucocorticoid treatment, the patient developed concurrent Sarcoptes scabiei and Candida albicans infection. The presence of the mite Sarcoptes scabiei and fungal elements was confirmed in skin scrapings. These infections arose as a result of weakened immunity after treatment.