Risk score to predict fibrosis among Mexican adults: results of the Health Workers Cohort Study

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Source: Frontiers Medicine

Original: https://www.frontiersin.org/articles/10.3389/fmed.2026.1699322...

Published: 2026-03-10T00:00:00Z

The Health Workers Cohort Study aimed to develop a simple noninvasive score to predict liver fibrosis in a Mexican population.[3] The study included 295 participants whose fibrosis was assessed using transient elastography (FibroScan).[3] The risk score developed included clinical and biochemical variables such as sex, triglycerides, glucose, waist circumference, hypertension, cholesterol, BMI, GGT enzyme, and insulin.[3] The new score achieved a diagnostic accuracy of 81.1% (95% CI, 74.4–87.7) in detecting fibrosis.[3] Compared with existing fibrosis scores, such as the BARD score and the AST/ALT ratio, the newly developed score demonstrated excellent diagnostic accuracy.[3] As a non-invasive tool, it may facilitate early identification of fibrosis in primary care and reduce the need for invasive liver biopsy.[3] However, the authors emphasize the need for further validation in larger and more diverse populations.[3]