Superagers Have Different Brains; Suicidality and Seizures; Brain Prize Winners

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Source: MedPage Today

Original: https://www.medpagetoday.com/neurology/generalneurology/120243...

Published: Tue, 10 Mar 2026 14:19:04 -0400

Superagers are adults over 80 years of age with extraordinary memory capacity. A study published in Nature showed that about twice as many new neurons were formed in their hippocampus compared to cognitively healthy older adults. At the same time, they create 2.5 times more young neurons than people with Alzheimer's disease. The brains of super-agers contain more newly developed neurons than the brains of younger adults in their 30s and 40s. Young neurons have a higher ability to grow, create new synaptic connections and integrate into brain networks. Astrocytes and CA1 neurons in superagers enhance synaptic signals in the hippocampus. This profile of neurogenesis shows resistance to aging.