Researchers have developed the weMERFISH platform for spatial transcriptomics of the entire zebrafish embryo at subcellular resolution.[1] Using it, they quantified the expression of 495 genes in whole embryos from gastrulation to organogenesis.[1] Integration with single-cell multiomics data produced an atlas with the expression of 25,872 genes and the accessibility of 294,954 chromatic regions, available online through the MERFISHEYES interface.[1] The temporal expression of genes coincides with cell maturation and morphogenetic movements.[1] Diverse expression patterns correspond to composites of tissue-specific accessible elements.[1] Changes in gene expression create sharp boundaries during gastrulation.[1] This method provides a comprehensive spatial atlas of gene expression and chromatic accessibility in the embryo.[1]