The study analyzed cancer incidence data from 185 countries and showed that four out of ten new cancer cases worldwide in 2022 (7.1 million out of 18.7 million) are due to 30 modifiable risk factors.[1][2][3] These factors include tobacco smoking, alcohol consumption, high body mass index, lack of exercise, smokeless tobacco products, inadequate breastfeeding, air pollution, ultraviolet radiation, 9 infectious agents, and 13 occupational exposures.[2][4][6] The most significant contributors were smoking (15.1%), infections (10.2%), and alcohol consumption (3.2%).[1][2][3] In men, 4.3 million cases (45.4%) and in women 2.7 million (29.7%) were due to these factors, with the proportion of preventable cancers varying by region from 24.6% to 38.2% for women and from 28.1% to 57.2% for men.[2][4] Approximately half of all preventable cancers were lung, stomach and cervical cancer.[1][2][3] The findings highlight the possibilities of prevention through targeted interventions adapted to regional and gender risk profiles.[6]