An atlas of exposome–phenome associations in health and disease risk

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Source: Nature Medicine

Original: https://www.nature.com/articles/s41591-026-04266-0...

Published: 2026-03-18

The study, titled "An atlas of exposome–phenome associations in health and disease risk," was published in Nature Medicine on March 18, 2026, with doi:10.1038/s41591-026-04266-0. Analyzes associations between 619 exposures and 305 quantitative phenotypes in health and disease risk. It is an exposure-wide association that identifies key factors influencing health traits. Blood lipids are among the major contributors to phenotypic health traits. Persistent pollutants contribute significantly to these properties. Vitamin E is another key contributor to phenotypic health characteristics. Thus, the atlas maps the connections of exposomes with phenomena in the context of health and risks.