A biomarker of Alzheimer’s disease could be a useful diagnostic tool for other amyloidoses

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Source: Nature Medicine

Original: https://www.nature.com/articles/s41591-026-04336-3...

Published: 2026-03-19

A new study published in the journal Nature Medicine shows that phosphorylated tau (p-tau) in the blood, previously used to diagnose Alzheimer's disease, could also serve as a biomarker for other types of systemic amyloidosis.[1] The research was conducted as a multicenter cross-sectional study and found that serum p-tau could help diagnose the most common forms of systemic amyloidosis.[1] The biomarker could also be useful in differentiating amyloidosis-related polyneuropathy from polyneuropathy due to other causes.[1] These findings suggest that p-tau has the potential to be a more versatile diagnostic tool than previously thought and may expand its use beyond the diagnosis of Alzheimer's disease.[1]