Artificial intelligence (AI) could safely exclude low-risk mammograms from radiological examination. Results of a prospective noninferiority study show that AI is able to identify low-risk mammograms. The study compared standard double-blind reading with an AI-assisted procedure. In the intervention group, AI assigned each mammogram a risk score from 1 to 10. Mammograms with low scores (≤5, later ≤7) were read by a single senior radiologist, while the others underwent a double reading. The study was conducted in Sweden on women aged 40-74 in four screening centers. Women were randomized to AI (Transpara v1.7.0) or standard double-reading without AI.[1]