[Articles] Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention

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Source: The Lancet

Original: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02637-6/fullt...

Published: 2026-03-21

The study, titled "Urinary stone prevention with hydration: a randomized clinical trial of an adherence intervention," investigated a behavioral intervention program to promote fluid intake. The program was aimed at secondary prevention of urinary stones. During the 2-year follow-up period, there was no reduction in recurrent stone events compared with guideline-based standard care. However, the intervention program slightly increased the urine volume of the patients. The study was a randomized clinical trial. The main finding is the failure to prevent relapses, despite the positive effect on hydration.