A study investigated the relationship between the ALDH2 rs671 genetic polymorphism and the risk of coronary atherosclerosis in patients with type 2 diabetes mellitus.[4] The research included 701 patients with type 2 diabetes mellitus (364 with coronary atherosclerosis and 337 without it) followed from January 2019 to February 2024.[4] The results showed that the G/A and A/A genotypes of the ALDH2 rs671 polymorphism were significantly more frequent in patients with coronary atherosclerosis compared to the control group.[4] Logistic regression analysis identified several risk factors: overweight (odds ratio 1.837), smoking (1.644), hypertension (2.007), dyslipidemia (1.809), and the presence of the G/A or A/A genotype of the ALDH2 rs671 polymorphism (1.564).[4] The study concluded that overweight, hypertension, dyslipidemia, and ALDH2 rs671 G/A or A/A genotype are associated with an increased risk of coronary atherosclerosis in patients with type 2 diabetes mellitus.[4]