The FAST randomized trial examined the effectiveness of a multidisciplinary home-based intervention to reduce falls in people up to 5 years post-stroke, aged over 50 years, able to walk 10m. The experimental group received functional exercise, home fall risk measures and mobility coaching from physiotherapists and occupational therapists for 6 months, while the control group received usual care. The primary outcome was the rate of falls over 12 months, the study enrolled 370 participants from three Australian states from August 2019 to December 2023. The intervention reduced the rate of falls by 33% (odds ratio 0.67, 95% CI 0.48–0.94; P=0.02), but did not affect the proportion of people with at least one fall (absolute risk reduction 0.03, 95% CI −0.07 to 0.13; P=0.52). The experimental group achieved improvements in community participation (mean difference 3%, 95% CI 1–6%; P=0.02), self-efficacy (0.6, 95% CI 0.2–1.0; P=0.004), walking speed (fast 0.13 m/s, P<0.001; preferred 0.06 m/s, 95% CI 0.02–0.10; P=0.02) and balance (step test 0.06 steps/s, 95% CI 0.01–0.12; P=0.03). These improvements have contributed to a reduction in falls. The study is registered under ACTRN12619001114134.