Most mass spectrometers handle a few molecules. This new prototype handles billions

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Source: ScienceDaily Health

Original: https://www.sciencedaily.com/releases/2026/03/260325005916.htm...

Published: Wed, 25 Mar 2026 21:30:50 EDT

Most mass spectrometers analyze molecules sequentially, only a few at a time, which is slow and insensitive to rare molecules.[1][2][3] A new prototype called MultiQ-IT can cool, capture, filter and redirect more than a billion ions simultaneously.[1][4] This system has 486 ports and can hold up to ten billion rounds, about a thousand times more than standard traps.[2] MultiQ-IT divides a single stream of ions into thousands of parallel processed parts.[2] Thanks to electrical barriers, it filters common interfering molecules and preserves rare biologically significant ones.[2] It achieves a 100-fold improvement in signal-to-noise ratio, revealing previously unseen proteins.[2] A study of this prototype was published in the journal Science Advances.[3] The results provide a blueprint for faster and more sensitive devices.[3]