A case-control study investigated the predictive value of fibrinogen-to-albumin ratio (FAR) for early missed miscarriage in 180 women with spontaneous abortion and 990 women with normal pregnancies. No significant differences were found in the levels of albumin, D-dimer, platelet count (PLT), mean platelet volume (MPV) and platelet-to-lymphocyte ratio (PLR) between groups (p > 0.05). In contrast, neutrophil to lymphocyte ratio (NLR), fibrinogen and FAR were significantly higher in the early missed abortion group (p < 0.05). The ROC curve analysis showed a sensitivity of 71.1% and a specificity of 74.4% for NLR at a cut-off value of 3.58. FAR had a higher sensitivity of 90% and specificity of 81.1% at a cut-off value of 0.008 for predicting early missed abortion. The study points to the role of prothrombotic conditions in the occurrence of early missed abortion.