Scientists discover “overflow valve” in cells linked to Parkinson’s Disease

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Source: ScienceDaily Health

Original: https://www.sciencedaily.com/releases/2026/03/260325005920.htm...

Published: Thu, 26 Mar 2026 07:35:07 EDT

Scientists have discovered an important ion channel called TMEM175 that acts as a flood valve in cells. This channel regulates acidity in lysosomes, which are cell bodies responsible for recycling and cleaning cells. When TMEM175 is working properly, it ensures that lysosomes work smoothly. If this channel is faulty or damaged, toxic substances can accumulate in the cells. This accumulation of toxic substances contributes to the development of Parkinson's disease. This discovery represents a new and promising target for the development of future treatments against Parkinson's disease.