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Immunosuppression-Associated Peripheral T-Cell Lymphoma

Source: NEJM

Original: https://www.nejm.org/doi/full/10.1056/NEJMicm2501877?af=R&rss=currentIssue...

Published: 2026-06-13T11:30:00Z

Immunosuppression-associated peripheral T-cell lymphoma is a rare type of blood cancer that develops in patients with a suppressed immune system. This condition occurs most frequently in people taking immunosuppressive medications after organ transplantation or for autoimmune diseases. The lymphoma originates from T-cells, which are an important component of the immune system. The disease manifests as abnormal growth of these cells in peripheral lymphoid tissues. Diagnosis is established through biopsy and histological examination. Treatment depends on the stage of the disease and the patient's overall condition. Prognosis varies depending on the type and extent of the disease.