The article published in the journal Science in June 2026 addresses the development of an HIV vaccine. It presents a scientific plan and strategy for creating an effective vaccine against this virus. The article is part of Volume 392, Issue 6804 of Science journal. An HIV vaccine could represent a significant breakthrough in combating this pandemic. Research in this field continues with the goal of developing a safe and effective protection against HIV infection. The vaccine blueprint is based on the latest knowledge from immunology and virology.