Emergency integrative supportive care program for frail patients with advanced pancreatic cancer: A prospective GERCOR ARCAD study

The study examined a 14-day emergency integrative supportive care program (14-EISCP) in 106 patients with advanced pancreatic cancer and poor performance status (PS≥2), aiming to improve pain control, nutrition, and preparation for chemotherapy. Of 93 evaluable patients (median age 76 years), the program was successful in 59.1% of patients. The program was feasible in 70.9% of cases and clinical benefit was observed in 79.6% of patients. After the program, chemotherapy was initiated within 30 days in 73.1% of patients, with 50% receiving combination chemotherapy. Median overall survival was 4.1 months. The program proved feasible and provides clinical benefit, enabling patients with advanced pancreatic cancer and poor performance status to access systemic therapy.