Effectiveness of the entire blood transfusion process with and without a clinical decision support system: a retrospective before-and-after study

The study evaluated the effectiveness of a clinical decision support system in improving management of the entire blood transfusion process. A closed-loop transfusion decision support system was developed and implemented hospital-wide in 2020 following a pilot phase. After implementation, completeness of transfusion records increased from 97.1% to 99.1%. Documentation time significantly decreased and nursing satisfaction significantly improved. A statistically significant difference was observed in the reported incidence of transfusion adverse reactions between the pre- and post-implementation periods. The system standardizes transfusion management, improves documentation completeness, reduces nursing workload, and enhances management of transfusion reactions.