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PROTEUS trial heralds perioperative therapy for prostate cancer

Source: Nature Medicine

Original: https://www.nature.com/articles/d41591-026-00032-4...

Published: 2026-06-22

The PROTEUS trial presents promising results in the field of prostate cancer treatment. It focuses on perioperative therapy, which is administered before and/or after surgical intervention. Specifically, it involves a combination of androgen-deprivation therapy (ADT) with the drug apalutamide. This combination could represent a new treatment option. It is intended for patients with high-risk, localized prostate cancer. The aim is to improve treatment outcomes for this patient group. If its efficacy is confirmed, this therapy could change standard procedures. It represents a significant advancement in the search for more effective methods to combat this disease.