According to a study published in JAMA Psychiatry, ketamine infusions may help treat major depressive episodes during the acute phase. The research focuses on the effectiveness of intravenously administered ketamine as a potential treatment approach. Ketamine is known for its rapid onset of action compared to traditional antidepressants. This meta-analysis collects and evaluates available evidence on the effectiveness of ketamine infusions. The results suggest the potential of ketamine as a treatment option for patients with severe depression. The study contributes to a better understanding of alternative approaches to treating depression.