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Microbial-based yeast protein is similar to whey protein and greater than collagen hydrolysate in supporting whole-body protein synthesis as determined by the indicatory amino acid oxidation method: a randomized controlled trial

Source: medRxiv

Original: https://www.medrxiv.org/content/10.64898/2026.06.13.26355601v1?rss=1...

Published: 2026-06-24

The study compared the effectiveness of three protein types in supporting whole-body protein synthesis: yeast-based protein (Saccharomyces cerevisiae), whey protein, and collagen hydrolysate. Thirteen healthy participants consumed protein beverages at 0.9 g per kilogram of body weight daily over eight hours. Researchers measured phenylalanine oxidation as an indicator of protein synthesis. Results showed that yeast protein and whey protein had similar effects on supporting protein synthesis and both were significantly more effective than collagen hydrolysate. No significant difference was found between whey and yeast protein. Protein type did not affect satiety or hunger scores. The study concludes that proteins rich in essential amino acids (whey and yeast protein) are similarly effective in supporting whole-body protein synthesis.