Two new compounds could reveal hidden drivers of Alzheimer’s disease

Vanderbilt University researchers developed the first selective compound designed to inhibit the TAOK-1 protein. This protein is currently poorly understood but is linked to Alzheimer's disease. Concurrently, they also discovered a second compound that activates the entire TAOK protein family. This second compound represents an unexpected new research tool for scientists. Together, these two compounds could help uncover hidden disease mechanisms. Their discovery might also suggest new treatment strategies for Alzheimer's disease.