This entry describes a completed clinical study. The study investigated the effect of a topical cream containing cetylated fatty acids. Its primary goal was to assess pain relief in patients suffering from knee osteoarthritis. Interventions included the application of Cetilar® Cream. A placebo cream was also used for comparison. The study focused specifically on individuals diagnosed with knee osteoarthritis. Pharmanutra S.p.a. sponsored this research. The study has concluded.