This article discusses a study investigating the effect of the intra-dialytic muscle energy technique. Specifically, the study focused on patients suffering from Restless Legs Syndrome (RLS). These patients also suffered from end-stage renal disease and were undergoing hemodialysis. The primary intervention involved the application of the muscle energy technique during dialysis. In addition, patients also received routine medical treatment and hemodialysis. The study was sponsored by Cairo University. The project was successfully completed.