The study examined the effects of permissive hypercapnia, a condition of elevated carbon dioxide levels in the blood during lung surgery, on inflammatory biomarkers in the human body. Researchers measured inflammatory markers in two types of samples: in blood serum and in fluid obtained by bronchoalveolar lavage from the lungs. Permissive hypercapnia is a technique sometimes used during operations to support lung function. The aim was to determine how this technique affects inflammatory processes in the body during surgical procedures. The study provides information on how inflammatory markers change in various body fluids when using this surgical technique. The results may help better understand the impact of permissive hypercapnia on the immune system during lung operations.