The Current State of Timely Results Reporting Among Hypertension Trials on ClinicalTrials.gov: A Cross-Sectional Meta-Research Analysis

The study analyzed 5,851 clinical trials focused on hypertension registered on ClinicalTrials.gov to assess how completely and promptly results are reported. Of 5,396 trials required to report results, only 9.1% reported timely (within 365 days of primary completion) and 28.8% reported at any time. Trials with confirmed reporting obligation achieved 36.9% timely reporting, while other trials only 6.3%. The presence of a United States site was most strongly associated with timely results reporting. Among unreported trials, 7.8% had sponsor-tagged publications and 36.4% under a broader definition. The research demonstrates that timely reporting of hypertension trial results remains uncommon and is most strongly associated with observable reporting obligations.