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Eplontersen for Transthyretin Amyloid Cardiomyopathy

Source: NEJM

Original: https://www.nejm.org/doi/full/10.1056/NEJMoa2608510?af=R&rss=currentIssue...

Published: 2026-08-28T09:00:00Z

Eplontersen is a new medication designed to treat transthyretin amyloid cardiomyopathy, a serious heart disease caused by the accumulation of amyloid proteins. This condition affects the heart muscle and leads to its progressive deterioration. The drug works by reducing the production of transthyretin, the protein responsible for forming amyloid deposits. The study was published in the prestigious medical journal New England Journal of Medicine. Eplontersen represents a new treatment option for patients with this serious and previously difficult-to-treat cardiomyopathy. The research is aimed at improving the prognosis and quality of life for patients with this condition.