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Duodenum inversum presenting with intestinal obstruction in a 40-day-old infant: a case report

Source: Frontiers Medicine

Original: https://www.frontiersin.org/articles/10.3389/fmed.2026.1923796...

Published: 2026-09-21T00:00:00Z

Duodenum inversum is a rare congenital anomaly characterized by an abnormal course of the duodenum with a normally positioned duodenojejunal junction. This case report describes a 40-day-old female infant presenting with recurrent postprandial vomiting and poor weight gain since birth. Initial clinical, metabolic, and ultrasonographic evaluations were unremarkable, excluding hypertrophic pyloric stenosis. Conservative management provided only temporary improvement. Upper gastrointestinal contrast study and endoscopy confirmed a reversed and tortuous duodenal course. Surgical exploration revealed fibrotic adhesions between the duodenum, colon, and retroperitoneum causing functional obstruction. Adhesiolysis restored normal duodenal anatomy. The patient recovered without complications and demonstrated normal growth at six-month follow-up.