MediNjuzMediNjuz Back to news list

Effect of Tranexamic Acid-Modified Leukocyte- and Platelet-Rich Fibrin on Hemostasis and Wound Healing After Tooth Extraction in Patients Receiving Direct Oral Anticoagulants: A Randomized Split-Mouth Clinical Study

Source: ClinicalTrials.gov

Original: https://clinicaltrials.gov/study/NCT07830875?aggFilters=status%3Acom%2CstudyType...

Published: Mon, 21 Sep 2026 00:00:00 EDT

This randomized split-mouth clinical study investigated the effect of tranexamic acid-modified leukocyte- and platelet-rich fibrin. The study focused on hemostasis and wound healing after tooth extraction. Patients receiving direct oral anticoagulants were included in the study. Interventions involved the application of tranexamic acid-modified leukocyte- and platelet-rich fibrin, as well as an absorbable gelatin sponge. The study was sponsored by Cumhuriyet University.