The article addresses the application of artificial intelligence in the diagnosis of Hirschsprung disease. Hirschsprung disease is a congenital disorder characterized by the absence of nerve cells in a portion of the large intestine, leading to defecation problems. Artificial intelligence represents a potential tool for improving the detection of this disease. The article was published in the prestigious New England Journal of Medicine in September 2026. The contribution focuses on the possibilities of modern technologies in diagnosing this serious congenital disorder. The use of AI may contribute to earlier and more accurate diagnosis.