Sex and gender differences belong in treatment guidelines

The article addresses the necessity of incorporating sex and gender differences into clinical guidelines and treatment procedures. Clinical guidelines should clearly state what is already known from available evidence, where evidence is lacking, and what information future clinical trials must include. Author Alexandra Kautzky-Willer from the Medical University of Vienna emphasizes the importance of systematically incorporating these differences into medical practice. The article was published in Nature Medicine in September 2026. The author declares no competing interests that could influence the work.