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[Editorial] Counteracting the rise of antimicrobial resistance in Shigella

Source: Lancet Infectious Diseases

Original: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00487-1/fullt...

Published: 2026-10

Shigella is a Gram-negative bacterium that causes shigellosis, characterized by intestinal symptoms. Shigellosis is among the leading causes of diarrheal disease deaths worldwide, particularly in children under 5 years of age. This infection disproportionately affects low- and middle-income countries, where transmission occurs mainly through the fecal-oral route due to poor water, sanitation, and hygiene conditions. Shigella is divided into four main species: S. dysenteriae, S. boydii, S. flexneri, and S. sonnei, all of which have multiple serotypes except S. flexneri.