This study investigated the impact of mobile health (mHealth) interventions on oral health-related quality of life in adult patients. It focused on individuals suffering from chronic systemic diseases. The conditions studied included Type 1 Diabetes Mellitus, Cardiovascular Diseases, Chronic Kidney Disease (stages 3b-5), and Hereditary Blood Disorders. The study compared two intervention methods: oral health education delivered via mHealth technologies and education provided through printed leaflets. The aim was to determine how these approaches affect patients' oral health and overall quality of life. The research was sponsored by King Faisal University and has been successfully completed.